Clinical Studies
SMILE Study 2023
Demonstrates greater reduction in MDS-UPDRS for a more extended period of time.
This study reflects the latest product improvements for patient and the physician ease of use.
Multi-center Duration Clinical Study 2022
Demonstrates immediate and long-lasting clinical MDS-UPDRS improvement
EarStim was tested for length of use in a pilot clinical trial in a number of centers in the USA.
Locomotion Study 2019
Provides immediate relief and accelerates impact of levodopa
The clinical trial conducted to measure the effect of using EarStim on the motor skills of Parkinson’s patients has been completed with positive results. The findings of the clinical trial were published in the Frontiers in Neurology journal. Please click here to access the article.
Mechanism of Action Study 2018
fMRI analysis demonstrates the modulation of multiple motor control regions of the brain which are all associated with PD pathophysiology and motor symptoms
EarStim’s mechanism of action in the brain was studied in a clinical trial. The patients’ fMRI images before and after the stimulation applied by EarStim were assessed to observe the changes.
Short-term efficacy study 2017
Demonstrates sustained UPDRS improvement at 50 minutes
The clinical trial conducted with 24 patients studied the efficacy and safety of EarStim in short-term use. The biostatistical analyses proved that EarStim alleviated some of the symptoms of the disease. Furthermore, no side effects were observed while wearing the device. The results of this research were published in an article in the journal Frontiers in Human Neuroscience. Please click here to access the article.
2017
Short-Term
Efficacy Study
2018
Mechanism of
Action Study
2019
Locomotion Study
2020
Pandemic
2021
Pandemic
2022
Multi-center
Duration
Clinical Study
2023
SMILE
Study
2024
Pivotal
Clinical Trial